ARTICLE - Voriconazole and atazanavir: a CYP2C19-dependent manageable drug-drug interaction

Four HIV-positive patients with pulmonary aspergillosis treated with voriconazole and atazanavir-based regimens

27/10/2014 - Four HIV-positive patients with pulmonary aspergillosis treated with voriconazole and atazanavir-based regimens (with or without ritonavir) were studied. They were managed by assessing their CYP2C19 genotype (CYP2C19*2, rs4244285, G>A, real-time PCR) and therapeutic drug monitoring (HPLC-based validation methods).

Voriconazole and atazanavir: a CYP2C19-dependent manageable drug-drug interaction

Calcagno A, Baietto L, Pagani N, Simiele M, Audagnotto S, D'Avolio A, De Rosa FG, Di Perri G, Bonora S.

Pharmacogenomics. 2014 Jul;15(10):1281-6.

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